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About RNAi Codex Codex provides a platform to collect and search short-hairpin RNA constructs (shRNAs) used for forward genetic screens. Current version of Codex includes shRNAs designed for all genes in human, mouse, rat and fruit fly genomes. It has extended the previous version of database by adding more shRNA constructs for each gene, and updating the gene annotation based on recent genome assembly. Users could search shRNAs based on the information of their interested genes. In the future, more shRNAs from other species will be collected, including Arabidopsis thaliana.
NewsNov 2009 - Arabidopsis shRNAs were added to Codex.
There are 8,868 shRNAs newly designed for 7,473 genes from TAIR collected into Codex. Please register to access arabidopsis shRNAs.July 2009 - Drosophila shRNAs were added to Codex.
There are 81,410 shRNAs newly designed for 22,863 genes from Flybase collected into Codex. Please register to access fruit fly shRNAs.June 2009 - Additional shRNAs from human, mouse, and rat genomes were added into Codex.
For each genes annotated in human (build 36.1), mouse (build 36) and rat (version 3.4) genomes, 6 new shRNAs were designed and collected into the new Codex database.May 2009 - Codex database schema was updated to version 3.0.
The new schema has updated the gene annotation based on the gene and transcripts information from NCBI. At the same time, the previous Codex database was integrated into the new schema.